COMPARATIVE STUDY BETWEEN THE EFFECTS OF HUMAN CD34 AND RAT BONE MARROW MESENCHYMAL STEM CELLS ON AMELIORATION OF CCL4 INDUCED LIVER FIBROSIS.

Document Type : Original Article

Authors

1 MEDICAL BIOCHEMSITRY AND MOLECULAR BIOLOGY , FACULTY OF MEDICINE, ASSUIT , EGYPT

2 MEDICAL BIOCHEMSITRY AND MOLECULAR BIOLOGY , FACULTY OF MEDICINE, CAIRO UNIVERSITY

3 PATHOLOGY DEPARTMENT, THEODOR BILHARZIA RESEARCH INSTITUTE, GIZA, EGYPT.

4 FACULTY OF MEDICINE, ASSUIT , EGYPT

5 ANATOMY DEPARTMENT, FACULTY OF MEDICINE, SOHAG UNIVEERSITY , SOHAG

Abstract

Human umbilical cord blood (UCB) cells and rat bone marrow
mesenchymal stem cells (BM-MSCs) have many advantages as grafts
for cell transplantation. The aim of this study was to investigate the
impact of UCB cells and BM-MSCs on reversal of hepatic injury and
revival of hepatic function in a rat model of carbon tetrachloride
(CCl4)-induced liver fibrosis.

Keywords